Patient information from Sydney IVF

PGD for genetic disorders

Preimplantation genetic diagnosis (PGD)

Fluorescently labelled DNA from the cells biopsied from a human embryo.

In a normal IVF cycle, the embryologist chooses which embryo will be transferred to the uterus based on a visual observation of the embryos as they develop.

Preimplantation genetic testing or diagnosis (PGD) allows the Sydney IVF scientist to base the choice on the results of genetic tests on the embryos to exclude those that contain an obvious genetic abnormality. Testing can involve a count of the chromosomes and/or a molecular examination for a particular gene or mutation. Either way, the testing can increase both the chance of a genetically normal pregnancy and your chance of having a baby.

Sydney IVF is one of the very few centres in Australia with the vital combination of IVF and genetics facilities to perform these sophisticated tests successfully.

Who can benefit from PGD?

PGD may be recommended for people who:

  • Are affected by or carry a known genetic disease
  • Have had recurrent miscarriages
  • Need to choose the sex of their baby for medical reasons.

Sydney IVF is evaluating the possible benefit of more routine PGD in increasing IVF live birth rates generally.